Cargando…

A Polymorphism in the Catalase Gene Promoter Confers Protection against Severe RSV Bronchiolitis

Respiratory syncytial virus (RSV) infection is associated with oxidative lung injury, decreased levels of antioxidant enzymes (AOEs), and the degradation of the transcription factor NF-E2-related factor 2 (NRF2), a master regulator of AOE expression. Single nucleotide polymorphisms (SNPs) in AOE and...

Descripción completa

Detalles Bibliográficos
Autores principales: Chambliss, Jeffrey M., Ansar, Maria, Kelley, John P., Spratt, Heidi, Garofalo, Roberto P., Casola, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019864/
https://www.ncbi.nlm.nih.gov/pubmed/31947722
http://dx.doi.org/10.3390/v12010057