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A Polymorphism in the Catalase Gene Promoter Confers Protection against Severe RSV Bronchiolitis
Respiratory syncytial virus (RSV) infection is associated with oxidative lung injury, decreased levels of antioxidant enzymes (AOEs), and the degradation of the transcription factor NF-E2-related factor 2 (NRF2), a master regulator of AOE expression. Single nucleotide polymorphisms (SNPs) in AOE and...
Autores principales: | Chambliss, Jeffrey M., Ansar, Maria, Kelley, John P., Spratt, Heidi, Garofalo, Roberto P., Casola, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019864/ https://www.ncbi.nlm.nih.gov/pubmed/31947722 http://dx.doi.org/10.3390/v12010057 |
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