An RNA Thermometer Activity of the West Nile Virus Genomic 3′-Terminal Stem-Loop Element Modulates Viral Replication Efficiency during Host Switching

The 3′-terminal stem-loop (3′SL) of the RNA genome of the flavivirus West Nile (WNV) harbors, in its stem, one of the sequence elements that are required for genome cyclization. As cyclization is a prerequisite for the initiation of viral replication, the 3′SL was proposed to act as a replication si...

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Detalles Bibliográficos
Autores principales: Meyer, Alexandra, Freier, Marie, Schmidt, Tobias, Rostowski, Katja, Zwoch, Juliane, Lilie, Hauke, Behrens, Sven-Erik, Friedrich, Susann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019923/
https://www.ncbi.nlm.nih.gov/pubmed/31952291
http://dx.doi.org/10.3390/v12010104

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