Using the LN34 Pan-Lyssavirus Real-Time RT-PCR Assay for Rabies Diagnosis and Rapid Genetic Typing from Formalin-Fixed Human Brain Tissue

Human rabies post mortem diagnostic samples are often preserved in formalin. While immunohistochemistry (IHC) has been routinely used for rabies antigen detection in formalin-fixed tissue, the formalin fixation process causes nucleic acid fragmentation that may affect PCR amplification. This study r...

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Detalles Bibliográficos
Autores principales: Condori, Rene Edgar, Niezgoda, Michael, Lopez, Griselda, Matos, Carmen Acosta, Mateo, Elinna Diaz, Gigante, Crystal, Hartloge, Claire, Filpo, Altagracia Pereira, Haim, Joseph, Satheshkumar, Panayampalli Subbian, Petersen, Brett, Wallace, Ryan, Olson, Victoria, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019996/
https://www.ncbi.nlm.nih.gov/pubmed/31963651
http://dx.doi.org/10.3390/v12010120

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