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DENV2 Pseudoviral Particles with Unprocessed Capsid Protein Are Assembled and Infectious

Proteolytic processing of flavivirus polyprotein is a uniquely controlled process. To date, the sequential cleavage of the capsid anchor sequence at the junction of C-PrM has been considered essential for the production of flaviviruses. In this study, we used two experimental approaches to show the...

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Detalles Bibliográficos
Autores principales: Rana, Jyoti, Burrone, Oscar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019998/
https://www.ncbi.nlm.nih.gov/pubmed/31881703
http://dx.doi.org/10.3390/v12010027