Cargando…

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP

African swine fever virus (ASFV) causes a contagious and frequently lethal disease of pigs with significant economic consequences to the swine industry. The ASFV genome encodes for more than 160 genes, but only a few of them have been studied in detail. Here we report the characterization of open re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramírez-Medina, Elizabeth, Vuono, Elizabeth A., Velazquez-Salinas, Lauro, Silva, Ediane, Rai, Ayushi, Pruitt, Sarah, Berggren, Keith A., Zhu, James, Borca, Manuel V., Gladue, Douglas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020080/ https://www.ncbi.nlm.nih.gov/pubmed/31947814 http://dx.doi.org/10.3390/v12010060

Ejemplares similares

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

Development and In Vivo Evaluation of a MGF110-1L Deletion Mutant in African Swine Fever Strain Georgia
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2021)

SERTA Domain Containing Protein 1 (SERTAD1) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2, Which Is Involved in Virus Virulence in Swine
por: Vuono, Elizabeth A., et al.
Publicado: (2020)

The C962R ORF of African Swine Fever Strain Georgia Is Non-Essential and Not Required for Virulence in Swine
por: Ramirez-Medina, Elizabeth., et al.
Publicado: (2020)

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene
por: Vuono, Elizabeth, et al.
Publicado: (2020)

Deletion of the ASFV dUTPase Gene E165R from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

Deletion of African Swine Fever Virus Histone-like Protein, A104R from the Georgia Isolate Drastically Reduces Virus Virulence in Domestic Pigs
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine
por: Gladue, Douglas P., et al.
Publicado: (2020)

Swine Host Protein Coiled-Coil Domain-Containing 115 (CCDC115) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2 during Virus Replication
por: Vuono, Elizabeth A., et al.
Publicado: (2020)

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

Deletion of an African Swine Fever Virus ATP-Dependent RNA Helicase QP509L from the Highly Virulent Georgia 2010 Strain Does Not Affect Replication or Virulence
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
por: Borca, Manuel V., et al.
Publicado: (2020)

Identification of a Continuously Stable and Commercially Available Cell Line for the Identification of Infectious African Swine Fever Virus in Clinical Samples
por: Rai, Ayushi, et al.
Publicado: (2020)

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever
por: Borca, Manuel V., et al.
Publicado: (2021)

ASFV Gene A151R Is Involved in the Process of Virulence in Domestic Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Differential Effect of the Deletion of African Swine Fever Virus Virulence-Associated Genes in the Induction of Attenuation of the Highly Virulent Georgia Strain
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2019)

Development Real-Time PCR Assays to Genetically Differentiate Vaccinated Pigs From Infected Pigs With the Eurasian Strain of African Swine Fever Virus
por: Velazquez-Salinas, Lauro, et al.
Publicado: (2021)

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence
por: Vuono, Elizabeth A., et al.
Publicado: (2021)

Evaluation of an ASFV RNA Helicase Gene A859L for Virus Replication and Swine Virulence
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2021)

Classical Swine Fever Virus Structural Glycoprotein E2 Interacts with Host Protein ACADM during the Virus Infectious Cycle
por: Vuono, Elizabeth, et al.
Publicado: (2023)

ASF Vaccine Candidate ASFV-G-∆I177L Does Not Exhibit Residual Virulence in Long-Term Clinical Studies
por: Borca, Manuel V., et al.
Publicado: (2023)

Evaluation of the Deletion of the African Swine Fever Virus Gene O174L from the Genome of the Georgia Isolate
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic
por: Velazquez-Salinas, Lauro, et al.
Publicado: (2020)

Evaluation of the Function of ASFV Gene E66L in the Process of Virus Replication and Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

African Swine Fever Vaccine Candidate ASFV-G-ΔI177L Produced in the Swine Macrophage-Derived Cell Line IPKM Remains Genetically Stable and Protective against Homologous Virulent Challenge
por: Borca, Manuel V., et al.
Publicado: (2023)

Complete Structural Predictions of the Proteome of African Swine Fever Virus Strain Georgia 2007
por: Spinard, Edward, et al.
Publicado: (2022)

Experimental Infection of Domestic Pigs with an African Swine Fever Virus Field Strain Isolated in 2021 from the Dominican Republic
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

The Presence of Virus Neutralizing Antibodies Is Highly Associated with Protection against Virulent Challenge in Domestic Pigs Immunized with ASFV live Attenuated Vaccine Candidates
por: Silva, Ediane B., et al.
Publicado: (2022)

Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge
por: Ding, Mingyang, et al.
Publicado: (2022)

Deletions of MGF110-9L and MGF360-9L from African swine fever virus are highly attenuated in swine and confer protection against homologous challenge
por: Li, Dan, et al.
Publicado: (2023)

The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β
por: Gao, Qi, et al.
Publicado: (2021)

Full genome sequence for the African swine fever virus outbreak in the Dominican Republic in 1980
por: Spinard, Edward, et al.
Publicado: (2023)

A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protect Pigs against a Virulent CSFV Challenge
por: Silva, Ediane, et al.
Publicado: (2023)

Construction, Identification and Analysis of the Interaction Network of African Swine Fever Virus MGF360-9L with Host Proteins
por: Yang, Bo, et al.
Publicado: (2021)

Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum
por: Gladue, Douglas P., et al.
Publicado: (2018)

African swine fever virus MGF360-9L promotes viral replication by degrading the host protein HAX1
por: Yang, Jinke, et al.
Publicado: (2023)

Interaction of Structural Glycoprotein E2 of Classical Swine Fever Virus with Protein Phosphatase 1 Catalytic Subunit Beta (PPP1CB)
por: Vuono, Elizabeth A., et al.
Publicado: (2019)

The SERTAD protein Taranis plays a role in Polycomb-mediated gene repression
por: Dutta, Pranabananda, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vquknhotp1bo8ssduqh7oritsu