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Mangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid Excretion

Hyperuricemia is characterized by abnormally high level of circulating uric acid in the blood and is associated with increased risk of kidney injury. The pathophysiological mechanisms leading to hyperuricemic nephropathy (HN) involve oxidative stress, endothelial dysfunction, inflammation, and fibro...

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Detalles Bibliográficos
Autores principales: Li, Xuechen, Yan, Zhenxin, Carlström, Mattias, Tian, Jinying, Zhang, Xiaolin, Zhang, Wenxuan, Wu, Song, Ye, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020245/
https://www.ncbi.nlm.nih.gov/pubmed/32116724
http://dx.doi.org/10.3389/fphar.2020.00049