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Estimation of an Appropriate Dose of Trazodone for Pediatric Insomnia and the Potential for a Trazodone–Atomoxetine Interaction

There is a paucity of clinical trials for the treatment of pediatric insomnia. This study was designed to predict the doses of trazodone to guide dosing in a clinical trial for pediatric insomnia using physiologically‐based pharmacokinetic (PBPK) modeling. Data on the pharmacokinetics of trazodone i...

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Detalles Bibliográficos
Autores principales:	Oggianu, Laura, Ke, Alice B., Chetty, Manoranjenni, Picollo, Rossella, Petrucci, Vanessa, Calisti, Fabrizio, Garofolo, Fabio, Tongiani, Serena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020267/ https://www.ncbi.nlm.nih.gov/pubmed/31808613 http://dx.doi.org/10.1002/psp4.12480

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