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Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice

Dried fruits of black goji were investigated for their fatty acid, mineral contents, and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice was revealed. It was observed that the key fatty acids from Lycium ruthenicum Murr. (LRM) oil studied included linoleic (59.38...

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Autores principales: Yossa Nzeuwa, Irma Belinda, Xia, Hui, Shi, Yuanyuan, Yang, Chao, Shah, Muhammad Waseem, Guo, Baofu, Wang, Liya, Sun, Guiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020293/
https://www.ncbi.nlm.nih.gov/pubmed/32148816
http://dx.doi.org/10.1002/fsn3.1393
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author Yossa Nzeuwa, Irma Belinda
Xia, Hui
Shi, Yuanyuan
Yang, Chao
Shah, Muhammad Waseem
Guo, Baofu
Wang, Liya
Sun, Guiju
author_facet Yossa Nzeuwa, Irma Belinda
Xia, Hui
Shi, Yuanyuan
Yang, Chao
Shah, Muhammad Waseem
Guo, Baofu
Wang, Liya
Sun, Guiju
author_sort Yossa Nzeuwa, Irma Belinda
collection PubMed
description Dried fruits of black goji were investigated for their fatty acid, mineral contents, and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice was revealed. It was observed that the key fatty acids from Lycium ruthenicum Murr. (LRM) oil studied included linoleic (59.38%), oleic (20.85%), palmitic (7.07%), linolenic (2.98%), and stearic acids (5.31%), which together comprised 95.59% of the total fatty acids. The key mineral nutrients studied were potassium (17,631.15 mg/kg), calcium (2004.4 mg/kg), and magnesium (1,274.6 mg/kg), while copper, iron, manganese, and zinc were found in trace. Moreover, oral administration of water extraction of LRM exhibited significant reduction of enzyme activities, and MDA level triggered by ISO to be near normal level, while exhibited a significant increase of SOD and GSH activities. Our results provide deep insight on LRM as a potential source of high‐value phytochemicals for the development of new functional food and beverage products.
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spelling pubmed-70202932020-03-06 Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice Yossa Nzeuwa, Irma Belinda Xia, Hui Shi, Yuanyuan Yang, Chao Shah, Muhammad Waseem Guo, Baofu Wang, Liya Sun, Guiju Food Sci Nutr Original Research Dried fruits of black goji were investigated for their fatty acid, mineral contents, and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice was revealed. It was observed that the key fatty acids from Lycium ruthenicum Murr. (LRM) oil studied included linoleic (59.38%), oleic (20.85%), palmitic (7.07%), linolenic (2.98%), and stearic acids (5.31%), which together comprised 95.59% of the total fatty acids. The key mineral nutrients studied were potassium (17,631.15 mg/kg), calcium (2004.4 mg/kg), and magnesium (1,274.6 mg/kg), while copper, iron, manganese, and zinc were found in trace. Moreover, oral administration of water extraction of LRM exhibited significant reduction of enzyme activities, and MDA level triggered by ISO to be near normal level, while exhibited a significant increase of SOD and GSH activities. Our results provide deep insight on LRM as a potential source of high‐value phytochemicals for the development of new functional food and beverage products. John Wiley and Sons Inc. 2020-01-07 /pmc/articles/PMC7020293/ /pubmed/32148816 http://dx.doi.org/10.1002/fsn3.1393 Text en © 2020 The Authors. Food Science & Nutrition published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Yossa Nzeuwa, Irma Belinda
Xia, Hui
Shi, Yuanyuan
Yang, Chao
Shah, Muhammad Waseem
Guo, Baofu
Wang, Liya
Sun, Guiju
Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
title Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
title_full Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
title_fullStr Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
title_full_unstemmed Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
title_short Fatty acid and mineral contents of Lycium ruthenicum Murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
title_sort fatty acid and mineral contents of lycium ruthenicum murr. and antioxidant activity against isoproterenol‐induced acute myocardial ischemia in mice
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020293/
https://www.ncbi.nlm.nih.gov/pubmed/32148816
http://dx.doi.org/10.1002/fsn3.1393
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