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Inflammasome Activation Induced by a Snake Venom Lys49-Phospholipase A(2) Homologue

Background: Snake venom phospholipases A(2) (PLA(2)s) have hemolytic, anticoagulant, myotoxic, oedematogenic, bactericidal, and inflammatory actions. BthTX-I, a Lys49-PLA(2) isolated from Bothrops jararacussu venom, is an example of Lys49-PLA(2) that presents such actions. NLRP3 is a cytosolic recep...

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Detalles Bibliográficos
Autores principales: Boeno, Charles Nunes, Paloschi, Mauro Valentino, Lopes, Jéssica Amaral, Pires, Weverson Luciano, Setúbal, Sulamita da Silva, Evangelista, Jaína Rodrigues, Soares, Andreimar Martins, Zuliani, Juliana Pavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020408/
https://www.ncbi.nlm.nih.gov/pubmed/31906173
http://dx.doi.org/10.3390/toxins12010022