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A Novel α(IIb)β(3) Antagonist from Snake Venom Prevents Thrombosis without Causing Bleeding
Life-threatening thrombocytopenia and bleeding, common side effects of clinically available α(IIb)β(3) antagonists, are associated with the induction of ligand-induced integrin conformational changes and exposure of ligand-induced binding sites (LIBSs). To address this issue, we examined intrinsic m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020592/ https://www.ncbi.nlm.nih.gov/pubmed/31877725 http://dx.doi.org/10.3390/toxins12010011 |