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Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis

AIMS: Neonatal tumors (NTs) include a group of diverse neoplasms. In this study, we reviewed our data for clinical presentations, management options, and outcome. MATERIALS AND METHODS: All patients from 0- to 1-month age presenting with solid tumors, from 2006 to 2018 were studied. The gender, pres...

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Autores principales: Solanki, Shailesh, Menon, Prema, Samujh, Ram, Gupta, Kirti, Rao, K. L. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020687/
https://www.ncbi.nlm.nih.gov/pubmed/32139986
http://dx.doi.org/10.4103/jiaps.JIAPS_241_18
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author Solanki, Shailesh
Menon, Prema
Samujh, Ram
Gupta, Kirti
Rao, K. L. N.
author_facet Solanki, Shailesh
Menon, Prema
Samujh, Ram
Gupta, Kirti
Rao, K. L. N.
author_sort Solanki, Shailesh
collection PubMed
description AIMS: Neonatal tumors (NTs) include a group of diverse neoplasms. In this study, we reviewed our data for clinical presentations, management options, and outcome. MATERIALS AND METHODS: All patients from 0- to 1-month age presenting with solid tumors, from 2006 to 2018 were studied. The gender, presentation, location, type of tumor, and management were analyzed. The final diagnosis was made with histopathology in all cases. Hemangiomas and lymphangiomas were excluded from the study. RESULTS: A total of 32 neonates were studied. The most common tumor was sacrococcygeal teratoma (SCT,16) followed by teratoma at other sites including two cases of fetus-in-fetu, soft-tissue sarcoma (STS, 4), mesenchymal hamartoma (2), hemangioendothelioma (2), and other rare tumors. Three tumors were diagnosed antenatally; of whom, two were neither visible externally nor palpable. Complete surgical excision was done for all except in a case of ovarian cyst where near-total cystectomy was done. No patient received chemotherapy or radiotherapy. Six patients had postoperative complications, including two who had local recurrence requiring excision. There was one mortality. All the other patients are doing well during follow-up. CONCLUSION: NTs have varied presentations. SCT and STS were the most common benign and malignant tumor, respectively. Early diagnosis and complete surgical excision are often curative for all, regardless of the pathology with the minimal role of chemotherapy or radiotherapy.
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spelling pubmed-70206872020-03-06 Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis Solanki, Shailesh Menon, Prema Samujh, Ram Gupta, Kirti Rao, K. L. N. J Indian Assoc Pediatr Surg Original Article AIMS: Neonatal tumors (NTs) include a group of diverse neoplasms. In this study, we reviewed our data for clinical presentations, management options, and outcome. MATERIALS AND METHODS: All patients from 0- to 1-month age presenting with solid tumors, from 2006 to 2018 were studied. The gender, presentation, location, type of tumor, and management were analyzed. The final diagnosis was made with histopathology in all cases. Hemangiomas and lymphangiomas were excluded from the study. RESULTS: A total of 32 neonates were studied. The most common tumor was sacrococcygeal teratoma (SCT,16) followed by teratoma at other sites including two cases of fetus-in-fetu, soft-tissue sarcoma (STS, 4), mesenchymal hamartoma (2), hemangioendothelioma (2), and other rare tumors. Three tumors were diagnosed antenatally; of whom, two were neither visible externally nor palpable. Complete surgical excision was done for all except in a case of ovarian cyst where near-total cystectomy was done. No patient received chemotherapy or radiotherapy. Six patients had postoperative complications, including two who had local recurrence requiring excision. There was one mortality. All the other patients are doing well during follow-up. CONCLUSION: NTs have varied presentations. SCT and STS were the most common benign and malignant tumor, respectively. Early diagnosis and complete surgical excision are often curative for all, regardless of the pathology with the minimal role of chemotherapy or radiotherapy. Wolters Kluwer - Medknow 2020 2020-01-28 /pmc/articles/PMC7020687/ /pubmed/32139986 http://dx.doi.org/10.4103/jiaps.JIAPS_241_18 Text en Copyright: © 2020 Journal of Indian Association of Pediatric Surgeons http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Solanki, Shailesh
Menon, Prema
Samujh, Ram
Gupta, Kirti
Rao, K. L. N.
Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis
title Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis
title_full Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis
title_fullStr Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis
title_full_unstemmed Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis
title_short Clinical Presentation and Surgical Management of Neonatal Tumors: Retrospective Analysis
title_sort clinical presentation and surgical management of neonatal tumors: retrospective analysis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020687/
https://www.ncbi.nlm.nih.gov/pubmed/32139986
http://dx.doi.org/10.4103/jiaps.JIAPS_241_18
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