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Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations
Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed to...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cardiologia - SBC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020871/ https://www.ncbi.nlm.nih.gov/pubmed/31691758 http://dx.doi.org/10.5935/abc.20190217 |
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author | Magalhães, Tiago Augusto Cury, Roberto Caldeira Cerci, Rodrigo Julio Parga Filho, José Rodrigues Gottlieb, Ilan Nacif, Marcelo Souto Pinto, Ibraim Masciarelli Rochitte, Carlos Eduardo Vilas-Boas, Fabio Schvartzman, Paulo R. |
author_facet | Magalhães, Tiago Augusto Cury, Roberto Caldeira Cerci, Rodrigo Julio Parga Filho, José Rodrigues Gottlieb, Ilan Nacif, Marcelo Souto Pinto, Ibraim Masciarelli Rochitte, Carlos Eduardo Vilas-Boas, Fabio Schvartzman, Paulo R. |
author_sort | Magalhães, Tiago Augusto |
collection | PubMed |
description | Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia. |
format | Online Article Text |
id | pubmed-7020871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Sociedade Brasileira de Cardiologia - SBC |
record_format | MEDLINE/PubMed |
spelling | pubmed-70208712020-02-20 Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations Magalhães, Tiago Augusto Cury, Roberto Caldeira Cerci, Rodrigo Julio Parga Filho, José Rodrigues Gottlieb, Ilan Nacif, Marcelo Souto Pinto, Ibraim Masciarelli Rochitte, Carlos Eduardo Vilas-Boas, Fabio Schvartzman, Paulo R. Arq Bras Cardiol Review Article Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia. Sociedade Brasileira de Cardiologia - SBC 2019-10 /pmc/articles/PMC7020871/ /pubmed/31691758 http://dx.doi.org/10.5935/abc.20190217 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Magalhães, Tiago Augusto Cury, Roberto Caldeira Cerci, Rodrigo Julio Parga Filho, José Rodrigues Gottlieb, Ilan Nacif, Marcelo Souto Pinto, Ibraim Masciarelli Rochitte, Carlos Eduardo Vilas-Boas, Fabio Schvartzman, Paulo R. Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title | Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_full | Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_fullStr | Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_full_unstemmed | Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_short | Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations |
title_sort | evaluation of myocardial perfusion by computed tomography - principles, technical background and recommendations |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020871/ https://www.ncbi.nlm.nih.gov/pubmed/31691758 http://dx.doi.org/10.5935/abc.20190217 |
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