Platelet Membrane-Coated Nanoparticles Target Sclerotic Aortic Valves in ApoE(−/−) Mice by Multiple Binding Mechanisms Under Pathological Shear Stress

BACKGROUND: Aortic valve disease is the most common valvular heart disease leading to valve replacement. The efficacy of pharmacological therapy for aortic valve disease is limited by the high mechanical stress at the aortic valves impairing the binding rate. We aimed to identify nanoparticle coatin...

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Detalles Bibliográficos
Autores principales: Yang, Hongbo, Song, Yanan, Chen, Jing, Pang, Zhiqing, Zhang, Ning, Cao, Jiatian, Wang, Qiaozi, Li, Qiyu, Zhang, Feng, Dai, Yuxiang, Li, Chenguang, Huang, Zheyong, Qian, Juying, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020933/
https://www.ncbi.nlm.nih.gov/pubmed/32103945
http://dx.doi.org/10.2147/IJN.S224024

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