Pharmacokinetics and safety of aztreonam/avibactam for the treatment of complicated intra-abdominal infections in hospitalized adults: results from the REJUVENATE study

OBJECTIVES: To investigate pharmacokinetics (PK) and safety (primary objectives) and efficacy (secondary objective) of the investigational monobactam/β-lactamase inhibitor combination aztreonam/avibactam in patients with complicated intra-abdominal infection (cIAI). METHODS: This Phase 2a open-label...

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Detalles Bibliográficos
Autores principales: Cornely, Oliver A, Cisneros, José M, Torre-Cisneros, Julian, Rodríguez-Hernández, María Jesús, Tallón-Aguilar, Luis, Calbo, Esther, Horcajada, Juan P, Queckenberg, Christian, Zettelmeyer, Ulrike, Arenz, Dorothee, Rosso-Fernández, Clara M, Jiménez-Jorge, Silvia, Turner, Guy, Raber, Susan, O’Brien, Seamus, Luckey, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021089/
https://www.ncbi.nlm.nih.gov/pubmed/31828337
http://dx.doi.org/10.1093/jac/dkz497

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