Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis

Antineutrophil cytoplasmic antibodies associated vasculitis (AAV) presenting with muscle weakness is rarely reported. We report a case of myeloperoxidase positive vasculitis presenting with severe proximal muscle weakness with normal creatine kinase and no positron-emission tomography uptake. There...

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Autores principales: Nagiah, Sureshkumar, Saranapala, Daunda Mudiyanselage Manodhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Unusual Presentation of More Common Disease/Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021126/
https://www.ncbi.nlm.nih.gov/pubmed/31969410
http://dx.doi.org/10.1136/bcr-2019-232854
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author Nagiah, Sureshkumar
Saranapala, Daunda Mudiyanselage Manodhi
author_facet Nagiah, Sureshkumar
Saranapala, Daunda Mudiyanselage Manodhi
author_sort Nagiah, Sureshkumar
collection PubMed
description Antineutrophil cytoplasmic antibodies associated vasculitis (AAV) presenting with muscle weakness is rarely reported. We report a case of myeloperoxidase positive vasculitis presenting with severe proximal muscle weakness with normal creatine kinase and no positron-emission tomography uptake. There was a significant delay in the diagnosis of AAV due to atypical presentation. We propose AAV be considered in the differential diagnosis of proximal muscle weakness after excluding the common causes.
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spelling pubmed-70211262020-02-28 Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis Nagiah, Sureshkumar Saranapala, Daunda Mudiyanselage Manodhi BMJ Case Rep Unusual Presentation of More Common Disease/Injury Antineutrophil cytoplasmic antibodies associated vasculitis (AAV) presenting with muscle weakness is rarely reported. We report a case of myeloperoxidase positive vasculitis presenting with severe proximal muscle weakness with normal creatine kinase and no positron-emission tomography uptake. There was a significant delay in the diagnosis of AAV due to atypical presentation. We propose AAV be considered in the differential diagnosis of proximal muscle weakness after excluding the common causes. BMJ Publishing Group 2020-01-21 /pmc/articles/PMC7021126/ /pubmed/31969410 http://dx.doi.org/10.1136/bcr-2019-232854 Text en © BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Unusual Presentation of More Common Disease/Injury
Nagiah, Sureshkumar
Saranapala, Daunda Mudiyanselage Manodhi
Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis
title Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis
title_full Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis
title_fullStr Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis
title_full_unstemmed Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis
title_short Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis
title_sort severe proximal muscle weakness with normal ck as a presenting feature of anca-associated vasculitis
topic Unusual Presentation of More Common Disease/Injury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021126/
https://www.ncbi.nlm.nih.gov/pubmed/31969410
http://dx.doi.org/10.1136/bcr-2019-232854
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