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Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women

BACKGROUND: Smoking is widely recognized as one of the most prevalent and preventable causes of many cancer types. This study aimed to quantify the population attributable fraction (PAF) of the lung cancer burden for smoking in Mongolia. METHODS: Lung cancer incidence and lung cancer-related death d...

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Autores principales: Tuvdendorj, Ariuntuya, Feenstra, Talitha, Tseveen, Badamsuren, Buskens, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021290/
https://www.ncbi.nlm.nih.gov/pubmed/32059049
http://dx.doi.org/10.1371/journal.pone.0229090
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author Tuvdendorj, Ariuntuya
Feenstra, Talitha
Tseveen, Badamsuren
Buskens, Erik
author_facet Tuvdendorj, Ariuntuya
Feenstra, Talitha
Tseveen, Badamsuren
Buskens, Erik
author_sort Tuvdendorj, Ariuntuya
collection PubMed
description BACKGROUND: Smoking is widely recognized as one of the most prevalent and preventable causes of many cancer types. This study aimed to quantify the population attributable fraction (PAF) of the lung cancer burden for smoking in Mongolia. METHODS: Lung cancer incidence and lung cancer-related death data came from the population-based national registry covering the period 2007–2016. Smoking prevalence data came from the STEPwise approach (STEP) national survey. The lung cancer-related disease burden was calculated and expressed in Disability Adjusted Life Years (DALYs) lost by gender and by year. This was combined with current smoking and former smoking prevalence data, and relative risks (RR) of lung cancer-related deaths for current smokers and former smokers versus never smokers from region-specific cohort studies to estimate the PAF of lung cancer attributable to “ever-smoking” in Mongolia. RESULTS: Between 2007 and 2016, lung cancer accounted for the loss of over 63,000 DALYs in Mongolia. The PAF of lung cancer-related deaths attributable to current and former smoking combined was 58.1% (95% IR = 43.1%-72.2%) for men and 8.9% (95% IR = 4.1% -13.5%) for women. Smoking-attributable DALYs loss amounted to 2589 years (95% IR = 1907–3226) in 2016. CONCLUSIONS: A considerable health loss may be prevented with an effective anti-smoking policy. In Mongolia, more than one third of lung cancer-related DALY loss is attributable to active smoking, and thus is potentially preventable. Furthermore, a gender-specific tobacco control policy may be worthwhile because of the large gender difference in smoking exposure in Mongolia. Next to this, age specific policy, including a smoke–free generation policy for adolescents, with targeted education, and mass media campaigns is needed.
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spelling pubmed-70212902020-02-26 Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women Tuvdendorj, Ariuntuya Feenstra, Talitha Tseveen, Badamsuren Buskens, Erik PLoS One Research Article BACKGROUND: Smoking is widely recognized as one of the most prevalent and preventable causes of many cancer types. This study aimed to quantify the population attributable fraction (PAF) of the lung cancer burden for smoking in Mongolia. METHODS: Lung cancer incidence and lung cancer-related death data came from the population-based national registry covering the period 2007–2016. Smoking prevalence data came from the STEPwise approach (STEP) national survey. The lung cancer-related disease burden was calculated and expressed in Disability Adjusted Life Years (DALYs) lost by gender and by year. This was combined with current smoking and former smoking prevalence data, and relative risks (RR) of lung cancer-related deaths for current smokers and former smokers versus never smokers from region-specific cohort studies to estimate the PAF of lung cancer attributable to “ever-smoking” in Mongolia. RESULTS: Between 2007 and 2016, lung cancer accounted for the loss of over 63,000 DALYs in Mongolia. The PAF of lung cancer-related deaths attributable to current and former smoking combined was 58.1% (95% IR = 43.1%-72.2%) for men and 8.9% (95% IR = 4.1% -13.5%) for women. Smoking-attributable DALYs loss amounted to 2589 years (95% IR = 1907–3226) in 2016. CONCLUSIONS: A considerable health loss may be prevented with an effective anti-smoking policy. In Mongolia, more than one third of lung cancer-related DALY loss is attributable to active smoking, and thus is potentially preventable. Furthermore, a gender-specific tobacco control policy may be worthwhile because of the large gender difference in smoking exposure in Mongolia. Next to this, age specific policy, including a smoke–free generation policy for adolescents, with targeted education, and mass media campaigns is needed. Public Library of Science 2020-02-14 /pmc/articles/PMC7021290/ /pubmed/32059049 http://dx.doi.org/10.1371/journal.pone.0229090 Text en © 2020 Tuvdendorj et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Tuvdendorj, Ariuntuya
Feenstra, Talitha
Tseveen, Badamsuren
Buskens, Erik
Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women
title Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women
title_full Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women
title_fullStr Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women
title_full_unstemmed Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women
title_short Smoking-attributable burden of lung cancer in Mongolia a data synthesis study on differences between men and women
title_sort smoking-attributable burden of lung cancer in mongolia a data synthesis study on differences between men and women
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021290/
https://www.ncbi.nlm.nih.gov/pubmed/32059049
http://dx.doi.org/10.1371/journal.pone.0229090
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