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Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers

BACKGROUND: DNA methylation at the fifth position of cytosine (5mC) is a common epigenetic alteration affecting a range of cellular processes. In recent years, 5-hydroxymethylcytosine (5hmC), an oxidized form of 5mC, has risen broad interests as a potential biomarker for lung cancer diagnosis and su...

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Detalles Bibliográficos
Autores principales: Wang, Zhihui, Du, Mulong, Yuan, Qianyu, Guo, Yichen, Hutchinson, John N., Su, Li, Zheng, Yinan, Wang, Jun, Mucci, Lorelei A., Lin, Xihong, Hou, Lifang, Christiani, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021546/
https://www.ncbi.nlm.nih.gov/pubmed/32062069
http://dx.doi.org/10.1016/j.neo.2020.01.001