Cargando…

Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers

BACKGROUND: DNA methylation at the fifth position of cytosine (5mC) is a common epigenetic alteration affecting a range of cellular processes. In recent years, 5-hydroxymethylcytosine (5hmC), an oxidized form of 5mC, has risen broad interests as a potential biomarker for lung cancer diagnosis and su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhihui, Du, Mulong, Yuan, Qianyu, Guo, Yichen, Hutchinson, John N., Su, Li, Zheng, Yinan, Wang, Jun, Mucci, Lorelei A., Lin, Xihong, Hou, Lifang, Christiani, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2020
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021546/ https://www.ncbi.nlm.nih.gov/pubmed/32062069 http://dx.doi.org/10.1016/j.neo.2020.01.001

Ejemplares similares

Genome-wide 5-hydroxymethylcytosine (5hmC) reassigned in Pten-depleted mESCs along neural differentiation
por: Wang, Zhangting, et al.
Publicado: (2022)

Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC)
por: Chu, Yajing, et al.
Publicado: (2018)

iRNA5hmC: The First Predictor to Identify RNA 5-Hydroxymethylcytosine Modifications Using Machine Learning
por: Liu, Yuan, et al.
Publicado: (2020)

5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection
por: Lu, Michael J., et al.
Publicado: (2022)

Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis
por: Guo, Xiao-Jun, et al.
Publicado: (2023)

Genome-wide 5-hydroxymethylcytosine (5hmC) emerges at early stage of in vitro differentiation of a putative hepatocyte progenitor
por: Rodríguez-Aguilera, Jesús Rafael, et al.
Publicado: (2020)

Impact of 5HydroxyMethylCytosine (5hmC) on reverse/direct association of cell-cycle, apoptosis, and extracellular matrix pathways in gastrointestinal cancers
por: Moravveji, Sayyed Sajjad, et al.
Publicado: (2022)

High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer
por: Strand, Siri H., et al.
Publicado: (2015)

Global DNA 5hmC and CK19(5hmC+) Contents: A Promising Biomarker for Predicting Prognosis in Small Hepatocellular Carcinoma
por: Jiang, Jinhua, et al.
Publicado: (2021)

Correlated 5-Hydroxymethylcytosine (5hmC) and Gene Expression Profiles Underpin Gene and Organ-Specific Epigenetic Regulation in Adult Mouse Brain and Liver
por: Lin, I-Hsuan, et al.
Publicado: (2017)

Exploring role of 5hmC as potential marker of chemoresistance
por: Kharat, Suhas S., et al.
Publicado: (2020)

De novo DNA methylation drives 5hmC accumulation in mouse zygotes
por: Amouroux, Rachel, et al.
Publicado: (2016)

Integrative Analysis of 5-Hydroxymethylcytosine and Transcriptional Profiling Identified 5hmC-Modified lncRNA Panel as Non-Invasive Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer
por: Li, Shuangquan, et al.
Publicado: (2022)

TET Enzymes and 5hmC in Adaptive and Innate Immune Systems
por: Lio, Chan-Wang J., et al.
Publicado: (2019)

5hmC modification regulates R-loop accumulation in response to stress
por: Xu, Xingyun, et al.
Publicado: (2023)

Combined methylation mapping of 5mC and 5hmC during early embryonic stages in bovine
por: de Montera, Béatrice, et al.
Publicado: (2013)

Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer
por: Storebjerg, Tine Maj, et al.
Publicado: (2018)

Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease
por: Stöger, Reinhard, et al.
Publicado: (2017)

New Insights into 5hmC DNA Modification: Generation, Distribution and Function
por: Shi, Dong-Qiao, et al.
Publicado: (2017)

Crystal structure of the 5hmC specific endonuclease PvuRts1I
por: Kazrani, Asgar Abbas, et al.
Publicado: (2014)

Alterations in the Genomic Distribution of 5hmC in In Vivo Aged Human Skin Fibroblasts
por: Kołodziej-Wojnar, Paulina, et al.
Publicado: (2020)

5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary
por: Khare, Tarang, et al.
Publicado: (2012)

IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC
por: Xu, Qiang, et al.
Publicado: (2016)

Values of 5mC, 5hmC, and TET2 for identifying the presence and progression of breast precancerous lesion
por: Zhang, Zijing, et al.
Publicado: (2019)

Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
por: Li, Chenying, et al.
Publicado: (2020)

Analysis of archaic human haplotypes suggests that 5hmC acts as an epigenetic guide for NCO recombination
por: Lee, Bernett, et al.
Publicado: (2022)

Standardized Computer-Assisted Analysis of 5-hmC Immunoreactivity in Dysplastic Nevi and Superficial Spreading Melanomas
por: Koch, Elias A. T., et al.
Publicado: (2023)

Alterations of the expression of TET2 and DNA 5-hmC predict poor prognosis in Myelodysplastic Neoplasms
por: Seethy, Ashikh A., et al.
Publicado: (2023)

5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?
por: Hysek, Martin, et al.
Publicado: (2023)

5mC and 5hmC dynamics during PGC reprogramming and role of Tet1 in female meiosis
por: Yamaguchi, Shinpei, et al.
Publicado: (2013)

Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain
por: Kuehner, Janise N, et al.
Publicado: (2023)

Cellular Composition and 5hmC Signature Predict the Treatment Response of AML Patients to Azacitidine Combined with Chemotherapy
por: Liang, Guanghao, et al.
Publicado: (2023)

i5hmCVec: Identifying 5-Hydroxymethylcytosine Sites of Drosophila RNA Using Sequence Feature Embeddings
por: Liu, Hang-Yu, et al.
Publicado: (2022)

Species-Specific 5 mC and 5 hmC Genomic Landscapes Indicate Epigenetic Contribution to Human Brain Evolution
por: Madrid, Andy, et al.
Publicado: (2018)

A Comparative Study on 5hmC Targeting Regulation of Neurons in AD Mice by Several Natural Compounds
por: Cao, Dongyi, et al.
Publicado: (2020)

Supplemental Herbal Choline Increases 5-hmC DNA on Whole Blood from Pregnant Ewes and Offspring
por: Roque-Jiménez, José Alejandro, et al.
Publicado: (2020)

TET2 Promotes Keloid Hyperplasia by Regulating 5hmC Modification in the TGFβ Promoter Region
por: Niu, Changying, et al.
Publicado: (2023)

Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells
por: Szulwach, Keith E., et al.
Publicado: (2011)

HPV infection and 5mC/5hmC epigenetic markers in penile squamous cell carcinoma: new insights into prognostics
por: Santos, Renan da Silva, et al.
Publicado: (2022)

Prenatal Lead (Pb) Exposure and Peripheral Blood DNA Methylation (5mC) and Hydroxymethylation (5hmC) in Mexican Adolescents from the ELEMENT Birth Cohort
por: Rygiel, Christine A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5j0n0f79aed438ivkkukufqe46