RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS

Translocated in liposarcoma (TLS)/fused in sarcoma (FUS) is a multitasking DNA/RNA binding protein implicated in cancer and neurodegenerative diseases. Upon DNA damage, TLS is recruited to the upstream region of the cyclin D1 gene (CCND1) through binding to the promotor associated non-coding RNA (pn...

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Detalles Bibliográficos
Autores principales: Hamad, Nesreen, Mashima, Tsukasa, Yamaoki, Yudai, Kondo, Keiko, Yoneda, Ryoma, Oyoshi, Takanori, Kurokawa, Riki, Nagata, Takashi, Katahira, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021683/
https://www.ncbi.nlm.nih.gov/pubmed/32060318
http://dx.doi.org/10.1038/s41598-020-59496-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021683/
https://www.ncbi.nlm.nih.gov/pubmed/32060318
http://dx.doi.org/10.1038/s41598-020-59496-0

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