Cargando…

Heterochromatin formation in Drosophila requires genome-wide histone deacetylation in cleavage chromatin before mid-blastula transition in early embryogenesis

Su(var) mutations define epigenetic factors controlling heterochromatin formation and gene silencing in Drosophila. Here, we identify SU(VAR)2-1 as a novel chromatin regulator that directs global histone deacetylation during the transition of cleavage chromatin into somatic blastoderm chromatin in e...

Descripción completa

Detalles Bibliográficos
Autores principales: Walther, Matthias, Schrahn, Sandy, Krauss, Veiko, Lein, Sandro, Kessler, Jeannette, Jenuwein, Thomas, Reuter, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021753/
https://www.ncbi.nlm.nih.gov/pubmed/31950239
http://dx.doi.org/10.1007/s00412-020-00732-x