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Structure of formylpeptide receptor 2-G(i) complex reveals insights into ligand recognition and signaling

Formylpeptide receptors (FPRs) as G protein-coupled receptors (GPCRs) can recognize formylpeptides derived from pathogens or host cells to function in host defense and cell clearance. In addition, FPRs, especially FPR2, can also recognize other ligands with a large chemical diversity generated at di...

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Detalles Bibliográficos
Autores principales: Zhuang, Youwen, Liu, Heng, Edward Zhou, X., Kumar Verma, Ravi, de Waal, Parker W., Jang, Wonjo, Xu, Ting-Hai, Wang, Lei, Meng, Xing, Zhao, Gongpu, Kang, Yanyong, Melcher, Karsten, Fan, Hao, Lambert, Nevin A., Eric Xu, H., Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021761/
https://www.ncbi.nlm.nih.gov/pubmed/32060286
http://dx.doi.org/10.1038/s41467-020-14728-9