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Structure of formylpeptide receptor 2-G(i) complex reveals insights into ligand recognition and signaling
Formylpeptide receptors (FPRs) as G protein-coupled receptors (GPCRs) can recognize formylpeptides derived from pathogens or host cells to function in host defense and cell clearance. In addition, FPRs, especially FPR2, can also recognize other ligands with a large chemical diversity generated at di...
Autores principales: | Zhuang, Youwen, Liu, Heng, Edward Zhou, X., Kumar Verma, Ravi, de Waal, Parker W., Jang, Wonjo, Xu, Ting-Hai, Wang, Lei, Meng, Xing, Zhao, Gongpu, Kang, Yanyong, Melcher, Karsten, Fan, Hao, Lambert, Nevin A., Eric Xu, H., Zhang, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021761/ https://www.ncbi.nlm.nih.gov/pubmed/32060286 http://dx.doi.org/10.1038/s41467-020-14728-9 |
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