Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma

Predicting the outcome of immunotherapy treatment in melanoma patients is challenging. Alterations in genes involved in antigen presentation and the interferon gamma (IFNγ) pathway play an important role in the immune response to tumors. We describe here that the overexpression of PSMB8 and PSMB9, t...

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Detalles Bibliográficos
Autores principales: Kalaora, Shelly, Lee, Joo Sang, Barnea, Eilon, Levy, Ronen, Greenberg, Polina, Alon, Michal, Yagel, Gal, Bar Eli, Gitit, Oren, Roni, Peri, Aviyah, Patkar, Sushant, Bitton, Lital, Rosenberg, Steven A., Lotem, Michal, Levin, Yishai, Admon, Arie, Ruppin, Eytan, Samuels, Yardena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021791/
https://www.ncbi.nlm.nih.gov/pubmed/32060274
http://dx.doi.org/10.1038/s41467-020-14639-9

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