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Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions

Inhibition of transcription caused by DNA damage-impaired RNA polymerase II (Pol II) elongation conceals a local increase in de novo transcription, slowly progressing from Transcription Start Sites (TSSs) to gene ends. Although associated with accelerated repair of Pol II-encountered lesions and lim...

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Detalles Bibliográficos
Autores principales: Liakos, Anastasios, Konstantopoulos, Dimitris, Lavigne, Matthieu D., Fousteri, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021815/
https://www.ncbi.nlm.nih.gov/pubmed/32060325
http://dx.doi.org/10.1038/s41467-020-14566-9