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Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions
Inhibition of transcription caused by DNA damage-impaired RNA polymerase II (Pol II) elongation conceals a local increase in de novo transcription, slowly progressing from Transcription Start Sites (TSSs) to gene ends. Although associated with accelerated repair of Pol II-encountered lesions and lim...
Autores principales: | Liakos, Anastasios, Konstantopoulos, Dimitris, Lavigne, Matthieu D., Fousteri, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021815/ https://www.ncbi.nlm.nih.gov/pubmed/32060325 http://dx.doi.org/10.1038/s41467-020-14566-9 |
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