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Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca
Melatonin is considered as the time-keeping hormone acting on important physiological functions of teleosts. While the influence of melatonin on reproduction and development is well described, its potential role on immune functions has little been considered. In order to better define an immune modu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021833/ https://www.ncbi.nlm.nih.gov/pubmed/32060347 http://dx.doi.org/10.1038/s41598-020-59568-1 |
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author | Baekelandt, Sébastien Milla, Sylvain Cornet, Valérie Flamion, Enora Ledoré, Yannick Redivo, Baptiste Antipine, Sascha Mandiki, Syaghalirwa N. M. Houndji, Alexis El Kertaoui, Najlae Kestemont, Patrick |
author_facet | Baekelandt, Sébastien Milla, Sylvain Cornet, Valérie Flamion, Enora Ledoré, Yannick Redivo, Baptiste Antipine, Sascha Mandiki, Syaghalirwa N. M. Houndji, Alexis El Kertaoui, Najlae Kestemont, Patrick |
author_sort | Baekelandt, Sébastien |
collection | PubMed |
description | Melatonin is considered as the time-keeping hormone acting on important physiological functions of teleosts. While the influence of melatonin on reproduction and development is well described, its potential role on immune functions has little been considered. In order to better define an immune modulation by the melatonin hormone, we hypothesized that natural variations of photoperiod and subsequent changes in melatonin release profile may act on immune status of pikeperch. Therefore, we investigated during 70 days the effects of two photoperiod regimes simulating the fall and spring in western Europe, on pikeperch physiological and immune responses. Samples were collected at 04:00 and 15:00 at days 1, 37 and 70. Growth, plasma melatonin levels, innate immune markers and expression of immune-relevant genes in head kidney tissue were assessed. While growth and stress level were not affected by the seasonal simulated photoperiods, nocturnal levels of plasma melatonin were photoperiod-dependent. Innate immune markers, including lysozyme, complement, peroxidase and phagocytic activities, were stimulated by the fall-simulated photoperiod and a significant correlation was made with plasma melatonin. In addition to bring the first evidence of changes in fish immunocompetence related to photoperiod, our results provide an additional indication supporting the immunomodulatory action of melatonin in teleosts. |
format | Online Article Text |
id | pubmed-7021833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-70218332020-02-24 Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca Baekelandt, Sébastien Milla, Sylvain Cornet, Valérie Flamion, Enora Ledoré, Yannick Redivo, Baptiste Antipine, Sascha Mandiki, Syaghalirwa N. M. Houndji, Alexis El Kertaoui, Najlae Kestemont, Patrick Sci Rep Article Melatonin is considered as the time-keeping hormone acting on important physiological functions of teleosts. While the influence of melatonin on reproduction and development is well described, its potential role on immune functions has little been considered. In order to better define an immune modulation by the melatonin hormone, we hypothesized that natural variations of photoperiod and subsequent changes in melatonin release profile may act on immune status of pikeperch. Therefore, we investigated during 70 days the effects of two photoperiod regimes simulating the fall and spring in western Europe, on pikeperch physiological and immune responses. Samples were collected at 04:00 and 15:00 at days 1, 37 and 70. Growth, plasma melatonin levels, innate immune markers and expression of immune-relevant genes in head kidney tissue were assessed. While growth and stress level were not affected by the seasonal simulated photoperiods, nocturnal levels of plasma melatonin were photoperiod-dependent. Innate immune markers, including lysozyme, complement, peroxidase and phagocytic activities, were stimulated by the fall-simulated photoperiod and a significant correlation was made with plasma melatonin. In addition to bring the first evidence of changes in fish immunocompetence related to photoperiod, our results provide an additional indication supporting the immunomodulatory action of melatonin in teleosts. Nature Publishing Group UK 2020-02-14 /pmc/articles/PMC7021833/ /pubmed/32060347 http://dx.doi.org/10.1038/s41598-020-59568-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Baekelandt, Sébastien Milla, Sylvain Cornet, Valérie Flamion, Enora Ledoré, Yannick Redivo, Baptiste Antipine, Sascha Mandiki, Syaghalirwa N. M. Houndji, Alexis El Kertaoui, Najlae Kestemont, Patrick Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca |
title | Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca |
title_full | Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca |
title_fullStr | Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca |
title_full_unstemmed | Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca |
title_short | Seasonal simulated photoperiods influence melatonin release and immune markers of pike perch Sander lucioperca |
title_sort | seasonal simulated photoperiods influence melatonin release and immune markers of pike perch sander lucioperca |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021833/ https://www.ncbi.nlm.nih.gov/pubmed/32060347 http://dx.doi.org/10.1038/s41598-020-59568-1 |
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