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Indocyanine Green-Nexturastat A-PLGA Nanoparticles Combine Photothermal and Epigenetic Therapy for Melanoma

In this study, we describe poly (lactic-co-glycolic) acid (PLGA)-based nanoparticles that combine photothermal therapy (PTT) with epigenetic therapy for melanoma. Specifically, we co-encapsulated indocyanine green (ICG), a PTT agent, and Nexturastat A (NextA), an epigenetic drug within PLGA nanopart...

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Detalles Bibliográficos
Autores principales: Ledezma, Debbie K., Balakrishnan, Preethi B., Cano-Mejia, Juliana, Sweeney, Elizabeth E., Hadley, Melissa, Bollard, Catherine M., Villagra, Alejandro, Fernandes, Rohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022377/
https://www.ncbi.nlm.nih.gov/pubmed/31963449
http://dx.doi.org/10.3390/nano10010161