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Mechanism and Improved Dissolution of Glycyrrhetinic Acid Solid Dispersion by Alkalizers

The purpose of this study was to increase the dissolution of glycyrrhetinic acid (GA) by preparing ternary solid dispersion (TSD) systems containing alkalizers, and to explore the modulating mechanism of alkalizers in solid dispersion systems. GA TSDs were prepared by hot melt extrusion (HME) with K...

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Detalles Bibliográficos
Autores principales:	Dong, Luning, Mai, Yaping, Liu, Qiang, Zhang, Wannian, Yang, Jianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022421/ https://www.ncbi.nlm.nih.gov/pubmed/31968604 http://dx.doi.org/10.3390/pharmaceutics12010082

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