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Effective Targeting of Colon Cancer Cells with Piperine Natural Anticancer Prodrug Using Functionalized Clusters of Hydroxyapatite Nanoparticles

Targeted drug delivery offers great opportunities for treating cancer. Here, we developed a novel anticancer targeted delivery system for piperine (Pip), an alkaloid prodrug derived from black pepper that exhibits anticancer effects. The tailored delivery system comprises aggregated hydroxyapatite n...

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Detalles Bibliográficos
Autores principales: AbouAitah, Khaled, Stefanek, Agata, Higazy, Iman M., Janczewska, Magdalena, Swiderska-Sroda, Anna, Chodara, Agnieszka, Wojnarowicz, Jacek, Szałaj, Urszula, Shahein, Samar A., Aboul-Enein, Ahmed M., Abou-Elella, Faten, Gierlotka, Stanislaw, Ciach, Tomasz, Lojkowski, Witold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022489/
https://www.ncbi.nlm.nih.gov/pubmed/31963155
http://dx.doi.org/10.3390/pharmaceutics12010070