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Fabrication of Intragastric Floating, Controlled Release 3D Printed Theophylline Tablets Using Hot-Melt Extrusion and Fused Deposition Modeling

This work presents a novel approach for producing gastro-retentive floating tablets (GRFT) by coupling hot-melt extrusion (HME) and fused deposition three-dimensional printing (3DP). Filaments containing theophylline (THEO) within a hydroxypropyl cellulose (HPC) matrix were prepared using HME. 3DP t...

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Detalles Bibliográficos
Autores principales:	Giri, Bhupendra Raj, Song, Eon Soo, Kwon, Jaewook, Lee, Ju-Hyun, Park, Jun-Bom, Kim, Dong Wuk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022551/ https://www.ncbi.nlm.nih.gov/pubmed/31963484 http://dx.doi.org/10.3390/pharmaceutics12010077

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