Amphiphilic Polypeptides for VEGF siRNA Delivery into Retinal Epithelial Cells

Polyethyleneimine, poly-L-lysine, chitosan and some others cationic polymers have been thoroughly studied as nucleic acid delivery systems in gene therapy. However, the drug release from these systems proceeds at a very low rate due to extremely high binding between a carrier and gene material. To r...

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Detalles Bibliográficos
Autores principales: Osipova, Olga, Sharoyko, Vladimir, Zashikhina, Natalia, Zakharova, Natalya, Tennikova, Tatiana, Urtti, Arto, Korzhikova-Vlakh, Evgenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022581/
https://www.ncbi.nlm.nih.gov/pubmed/31906576
http://dx.doi.org/10.3390/pharmaceutics12010039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022581/
https://www.ncbi.nlm.nih.gov/pubmed/31906576
http://dx.doi.org/10.3390/pharmaceutics12010039

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