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Amphiphilic Polypeptides for VEGF siRNA Delivery into Retinal Epithelial Cells
Polyethyleneimine, poly-L-lysine, chitosan and some others cationic polymers have been thoroughly studied as nucleic acid delivery systems in gene therapy. However, the drug release from these systems proceeds at a very low rate due to extremely high binding between a carrier and gene material. To r...
Autores principales: | Osipova, Olga, Sharoyko, Vladimir, Zashikhina, Natalia, Zakharova, Natalya, Tennikova, Tatiana, Urtti, Arto, Korzhikova-Vlakh, Evgenia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022581/ https://www.ncbi.nlm.nih.gov/pubmed/31906576 http://dx.doi.org/10.3390/pharmaceutics12010039 |
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