Cargando…

Unification of Opposites between Two Antioxidant Transcription Factors Nrf1 and Nrf2 in Mediating Distinct Cellular Responses to the Endoplasmic Reticulum Stressor Tunicamycin

The water-soluble Nrf2 (nuclear factor, erythroid 2-like 2, also called Nfe2l2) is accepted as a master regulator of antioxidant responses to cellular stress, and it was also identified as a direct target of the endoplasmic reticulum (ER)-anchored PERK (protein kinase RNA-like endoplasmic reticulum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yu-ping, Zheng, Ze, Hu, Shaofan, Ru, Xufang, Fan, Zhuo, Qiu, Lu, Zhang, Yiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022656/ https://www.ncbi.nlm.nih.gov/pubmed/31861550 http://dx.doi.org/10.3390/antiox9010004

Ejemplares similares

Distinct Roles of Nrf1 and Nrf2 in Monitoring the Reductive Stress Response to Dithiothreitol (DTT)
por: Wufuer, Reziyamu, et al.
Publicado: (2022)

Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor
por: Qiu, Lu, et al.
Publicado: (2018)

Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes
por: Wang, Meng, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress Inducer Tunicamycin Alters Hepatic Energy Homeostasis in Mice
por: Feng, Bin, et al.
Publicado: (2017)

Differential Yet Integral Contributions of Nrf1 and Nrf2 in the Human HepG2 Cells on Antioxidant Cytoprotective Response against Tert-Butylhydroquinone as a Pro-Oxidative Stressor
por: Wufuer, Reziyamu, et al.
Publicado: (2021)

Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks
por: Zhang, Shuwei, et al.
Publicado: (2020)

Effects of Escitalopram on Endoplasmic Reticulum Stress and Oxidative Stress Induced by Tunicamycin
por: Yang, Lixia, et al.
Publicado: (2021)

The endoplasmic reticulum stress induced by tunicamycin affects the viability and autophagy activity of chondrocytes
por: Wu, Hao, et al.
Publicado: (2020)

Tunicamycin-Induced Endoplasmic Reticulum Stress Damages Complex I in Cardiac Mitochondria
por: Chen, Qun, et al.
Publicado: (2022)

Reduced glutathione alleviates tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos
por: ALI, Ihsan, et al.
Publicado: (2017)

Overexpression of GRP78/BiP in P-Glycoprotein-Positive L1210 Cells is Responsible for Altered Response of Cells to Tunicamycin as a Stressor of the Endoplasmic Reticulum
por: Šereš, Mário, et al.
Publicado: (2020)

Induction of Liver Steatosis in BAP31-Deficient Mice Burdened with Tunicamycin-Induced Endoplasmic Reticulum Stress
por: Wu, Zhenhua, et al.
Publicado: (2018)

TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2
por: Wang, Meng, et al.
Publicado: (2021)

ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress
por: Sarcinelli, Carmen, et al.
Publicado: (2020)

Tunicamycin-induced Endoplasmic Reticulum Stress Upregulates the Expression of Pentraxin 3 in Human Retinal Pigment Epithelial Cells
por: Hwang, Narae, et al.
Publicado: (2016)

Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1
por: Guha, Prasun, et al.
Publicado: (2017)

Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma
por: Zhao, Guohong, et al.
Publicado: (2020)

Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks
por: Hu, Shaofan, et al.
Publicado: (2022)

Pharmacological Activation of Nrf2 by Rosolic Acid Attenuates Endoplasmic Reticulum Stress in Endothelial Cells
por: Naresh Amin, Karan, et al.
Publicado: (2021)

The Influence of Nrf2 on Cardiac Responses to Environmental Stressors
por: Howden, Reuben, et al.
Publicado: (2013)

SMURF1 attenuates endoplasmic reticulum stress by promoting the degradation of KEAP1 to activate NRF2 antioxidant pathway
por: Dong, Lei, et al.
Publicado: (2023)

HTLV-1 infected CD4+T cells of HAM/TSP patients are susceptible to tunicamycin-induced endoplasmic reticulum stress
por: Kodama, Daisuke, et al.
Publicado: (2015)

Taurine Ameliorates Tunicamycin-Induced Liver Injury by Disrupting the Vicious Cycle between Oxidative Stress and Endoplasmic Reticulum Stress
por: Kim, Sou Hyun, et al.
Publicado: (2022)

Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma
por: Chen, Feilong, et al.
Publicado: (2022)

Bifidobacteria Prevent Tunicamycin-Induced Endoplasmic Reticulum Stress and Subsequent Barrier Disruption in Human Intestinal Epithelial Caco-2 Monolayers
por: Akiyama, Takuya, et al.
Publicado: (2016)

Tunicamycin Induces Hepatic Stellate Cell Apoptosis Through Calpain-2/Ca(2 +)-Dependent Endoplasmic Reticulum Stress Pathway
por: Liu, Haiying, et al.
Publicado: (2021)

Glucocorticoids protect HEI-OC1 cells from tunicamycin-induced cell damage via inhibiting endoplasmic reticulum stress
por: Liu, Zhibiao, et al.
Publicado: (2021)

Glucose Starvation-Induced Rapid Death of Nrf1α-Deficient, but Not Nrf2-Deficient, Hepatoma Cells Results from Its Fatal Defects in the Redox Metabolism Reprogramming
por: Zhu, Yu-ping, et al.
Publicado: (2020)

Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway
por: Guo, Jingru, et al.
Publicado: (2022)

Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells
por: Liu, Keli, et al.
Publicado: (2023)

TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells
por: Ren, Yonggang, et al.
Publicado: (2016)

Deficiency in the double-stranded RNA binding protein HYPONASTIC LEAVES1 increases sensitivity to the endoplasmic reticulum stress inducer tunicamycin in Arabidopsis
por: Hirata, Rikako, et al.
Publicado: (2019)

Interplay between P-Glycoprotein Expression and Resistance to Endoplasmic Reticulum Stressors
por: Hano, Milan, et al.
Publicado: (2018)

Nrf1 Is Endowed with a Dominant Tumor-Repressing Effect onto the Wnt/β-Catenin-Dependent and Wnt/β-Catenin-Independent Signaling Networks in the Human Liver Cancer
por: Chen, Jiayu, et al.
Publicado: (2020)

Resveratrol Alleviates the Inhibitory Effect of Tunicamycin-Induced Endoplasmic Reticulum Stress on Expression of Genes Involved in Thyroid Hormone Synthesis in FRTL-5 Thyrocytes
por: Wen, Gaiping, et al.
Publicado: (2021)

EETs alleviate alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress through the Trim25/Keap1/Nrf2 axis
por: Zhang, Chen-Yu, et al.
Publicado: (2023)

Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity
por: Lehrbach, Nicolas J, et al.
Publicado: (2019)

BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor
por: Cheung, Timothy P., et al.
Publicado: (2020)

Salinomycin triggers prostate cancer cell apoptosis by inducing oxidative and endoplasmic reticulum stress via suppressing Nrf2 signaling
por: Yu, Jianyong, et al.
Publicado: (2021)

Partial replacement of high-fat diet with n-3 PUFAs enhanced beef tallow attenuates dyslipidemia and endoplasmic reticulum stress in tunicamycin-injected rats
por: Zheng, Jiaxiang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k3l4un8asq433c66h93n8d0oa9