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Development of Human Monoclonal Antibody for Claudin-3 Overexpressing Carcinoma Targeting

Most malignant tumors originate from epithelial tissues in which tight junctions mediate cell–cell interactions. Tight junction proteins, especially claudin-3 (CLDN3), are overexpressed in various cancers. Claudin-3 is exposed externally during tumorigenesis making it a potential biomarker and thera...

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Detalles Bibliográficos
Autores principales:	Yang, Hobin, Park, Hayeon, Lee, Yong Jin, Choi, Jun Young, Kim, TaeEun, Rajasekaran, Nirmal, Lee, Saehyung, Song, Kyoung, Hong, Sungyoul, Choi, Joon-Seok, Shim, Hyunbo, Kim, Young-Deug, Hwang, Soohyun, Choi, Yoon-La, Shin, Young Kee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022679/ https://www.ncbi.nlm.nih.gov/pubmed/31905631 http://dx.doi.org/10.3390/biom10010051

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