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Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties

This article provides an overview of current research into the development, synthesis, photocatalytic bacterial activity, biocompatibility and cytotoxic properties of various visible-light active titanium dioxide (TiO(2)) nanoparticles (NPs) and their nanocomposites. To achieve antibacterial inactiv...

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Detalles Bibliográficos
Autores principales: Liao, Chengzhu, Li, Yuchao, Tjong, Sie Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022691/
https://www.ncbi.nlm.nih.gov/pubmed/31936581
http://dx.doi.org/10.3390/nano10010124
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author Liao, Chengzhu
Li, Yuchao
Tjong, Sie Chin
author_facet Liao, Chengzhu
Li, Yuchao
Tjong, Sie Chin
author_sort Liao, Chengzhu
collection PubMed
description This article provides an overview of current research into the development, synthesis, photocatalytic bacterial activity, biocompatibility and cytotoxic properties of various visible-light active titanium dioxide (TiO(2)) nanoparticles (NPs) and their nanocomposites. To achieve antibacterial inactivation under visible light, TiO(2) NPs are doped with metal and non-metal elements, modified with carbonaceous nanomaterials, and coupled with other metal oxide semiconductors. Transition metals introduce a localized d-electron state just below the conduction band of TiO(2) NPs, thereby narrowing the bandgap and causing a red shift of the optical absorption edge into the visible region. Silver nanoparticles of doped TiO(2) NPs experience surface plasmon resonance under visible light excitation, leading to the injection of hot electrons into the conduction band of TiO(2) NPs to generate reactive oxygen species (ROS) for bacterial killing. The modification of TiO(2) NPs with carbon nanotubes and graphene sheets also achieve the efficient creation of ROS under visible light irradiation. Furthermore, titanium-based alloy implants in orthopedics with enhanced antibacterial activity and biocompatibility can be achieved by forming a surface layer of Ag-doped titania nanotubes. By incorporating TiO(2) NPs and Cu-doped TiO(2) NPs into chitosan or the textile matrix, the resulting polymer nanocomposites exhibit excellent antimicrobial properties that can have applications as fruit/food wrapping films, self-cleaning fabrics, medical scaffolds and wound dressings. Considering the possible use of visible-light active TiO(2) nanomaterials for various applications, their toxicity impact on the environment and public health is also addressed.
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spelling pubmed-70226912020-03-09 Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties Liao, Chengzhu Li, Yuchao Tjong, Sie Chin Nanomaterials (Basel) Review This article provides an overview of current research into the development, synthesis, photocatalytic bacterial activity, biocompatibility and cytotoxic properties of various visible-light active titanium dioxide (TiO(2)) nanoparticles (NPs) and their nanocomposites. To achieve antibacterial inactivation under visible light, TiO(2) NPs are doped with metal and non-metal elements, modified with carbonaceous nanomaterials, and coupled with other metal oxide semiconductors. Transition metals introduce a localized d-electron state just below the conduction band of TiO(2) NPs, thereby narrowing the bandgap and causing a red shift of the optical absorption edge into the visible region. Silver nanoparticles of doped TiO(2) NPs experience surface plasmon resonance under visible light excitation, leading to the injection of hot electrons into the conduction band of TiO(2) NPs to generate reactive oxygen species (ROS) for bacterial killing. The modification of TiO(2) NPs with carbon nanotubes and graphene sheets also achieve the efficient creation of ROS under visible light irradiation. Furthermore, titanium-based alloy implants in orthopedics with enhanced antibacterial activity and biocompatibility can be achieved by forming a surface layer of Ag-doped titania nanotubes. By incorporating TiO(2) NPs and Cu-doped TiO(2) NPs into chitosan or the textile matrix, the resulting polymer nanocomposites exhibit excellent antimicrobial properties that can have applications as fruit/food wrapping films, self-cleaning fabrics, medical scaffolds and wound dressings. Considering the possible use of visible-light active TiO(2) nanomaterials for various applications, their toxicity impact on the environment and public health is also addressed. MDPI 2020-01-09 /pmc/articles/PMC7022691/ /pubmed/31936581 http://dx.doi.org/10.3390/nano10010124 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liao, Chengzhu
Li, Yuchao
Tjong, Sie Chin
Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties
title Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties
title_full Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties
title_fullStr Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties
title_full_unstemmed Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties
title_short Visible-Light Active Titanium Dioxide Nanomaterials with Bactericidal Properties
title_sort visible-light active titanium dioxide nanomaterials with bactericidal properties
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022691/
https://www.ncbi.nlm.nih.gov/pubmed/31936581
http://dx.doi.org/10.3390/nano10010124
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