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Dissolution Advantage of Nitazoxanide Cocrystals in the Presence of Cellulosic Polymers

The effect of hydroxypropyl methylcellulose (HPMC) and methylcellulose (Methocel(®) 60 HG) on the dissolution behavior of two cocrystals derived from nitazoxanide (NTZ), viz., nitazoxanide-glutaric acid (NTZ-GLU, 1:1) and nitazoxanide-succinic acid (NTZ-SUC, 2:1), was explored. Powder dissolution ex...

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Detalles Bibliográficos
Autores principales: Salas-Zúñiga, Reynaldo, Rodríguez-Ruiz, Christian, Höpfl, Herbert, Morales-Rojas, Hugo, Sánchez-Guadarrama, Obdulia, Rodríguez-Cuamatzi, Patricia, Herrera-Ruiz, Dea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022799/
https://www.ncbi.nlm.nih.gov/pubmed/31881696
http://dx.doi.org/10.3390/pharmaceutics12010023

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