Cargando…

Interaction of a Novel Zn2Cys6 Transcription Factor DcGliZ with Promoters in the Gliotoxin Biosynthetic Gene Cluster of the Deep-Sea-Derived Fungus Dichotomomyces cejpii

Gliotoxin is an important epipolythiodioxopiperazine, which was biosynthesized by the gli gene cluster in Aspergillus genus. However, the regulatory mechanism of gliotoxin biosynthesis remains unclear. In this study, a novel Zn2Cys6 transcription factor DcGliZ that is responsible for the regulation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Zi-Lei, Ye, Wei, Zhu, Mu-Zi, Kong, Ya-Li, Li, Sai-Ni, Liu, Shan, Zhang, Wei-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022936/ https://www.ncbi.nlm.nih.gov/pubmed/31905743 http://dx.doi.org/10.3390/biom10010056

Ejemplares similares

De Novo Transcriptome Sequencing of the Deep-Sea-Derived Fungus Dichotomomyces cejpii and Analysis of Gliotoxin Biosynthesis Genes
por: Ye, Wei, et al.
Publicado: (2018)

Dechdigliotoxins A–C, Three Novel Disulfide-Bridged Gliotoxin Dimers from Deep-Sea Sediment Derived Fungus Dichotomomyces cejpii
por: Liu, Zhaoming, et al.
Publicado: (2019)

Epipolythiodiketopiperazines from the Marine Derived Fungus Dichotomomyces cejpii with NF-κB Inhibitory Potential
por: Harms, Henrik, et al.
Publicado: (2015)

Diverse Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces cejpii F31-1
por: Chen, Yan-Xiu, et al.
Publicado: (2017)

Dichotocejpins A–C: New Diketopiperazines from a Deep-Sea-Derived Fungus Dichotomomyces cejpii FS110
por: Fan, Zhen, et al.
Publicado: (2016)

Polyketides and Alkaloids from the Marine-Derived Fungus Dichotomomyces cejpii F31-1 and the Antiviral Activity of Scequinadoline A against Dengue Virus
por: Wu, Dong-Lan, et al.
Publicado: (2018)

Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin
por: Schrettl, Markus, et al.
Publicado: (2010)

The Toxic Mechanism of Gliotoxins and Biosynthetic Strategies for Toxicity Prevention
por: Ye, Wei, et al.
Publicado: (2021)

The evolution of the gliotoxin biosynthetic gene cluster in Penicillium fungi
por: Balamurugan, Charu, et al.
Publicado: (2023)

Secondary Metabolites from the Marine-Derived Fungus Dichotomomyces sp. L-8 and Their Cytotoxic Activity
por: Huang, Li-Hong, et al.
Publicado: (2017)

Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity
por: Smith, Elizabeth B., et al.
Publicado: (2016)

Host immune status-specific production of gliotoxin and bis-methyl-gliotoxin during invasive aspergillosis in mice
por: Sugui, Janyce A., et al.
Publicado: (2017)

Effect of gliotoxin on human polymorphonuclear neutrophils.
por: Shah, D T, et al.
Publicado: (1998)

Gliotoxin Isolated from Marine Fungus Aspergillus sp. Induces Apoptosis of Human Cervical Cancer and Chondrosarcoma Cells
por: Nguyen, Van-Tinh, et al.
Publicado: (2013)

The Role of Zinc in Gliotoxin Biosynthesis of Aspergillus fumigatus
por: Seo, Hyewon, et al.
Publicado: (2019)

Regulation of gliotoxin biosynthesis and protection in Aspergillus species
por: de Castro, Patrícia Alves, et al.
Publicado: (2022)

Frequency of KRAS p.Gly12Cys Mutation in Brazilian Patients With Lung Cancer
por: Cavagna, Rodrigo, et al.
Publicado: (2021)

Gliotoxin Aggravates Experimental Autoimmune Encephalomyelitis by Triggering Neuroinflammation
por: Fraga-Silva, Thais Fernanda de Campos, et al.
Publicado: (2019)

Structural and Mechanistic Insights into C−S Bond Formation in Gliotoxin
por: Scherlach, Kirstin, et al.
Publicado: (2021)

Tpc1 is an important Zn(II)(2)Cys(6) transcriptional regulator required for polarized growth and virulence in the rice blast fungus
por: Galhano, Rita, et al.
Publicado: (2017)

Dual Role of a Biosynthetic Enzyme, CysK, in Contact Dependent Growth Inhibition in Bacteria
por: Kaundal, Soni, et al.
Publicado: (2016)

Systematic Analysis of Zn(2)Cys(6) Transcription Factors Required for Development and Pathogenicity by High-Throughput Gene Knockout in the Rice Blast Fungus
por: Lu, Jianping, et al.
Publicado: (2014)

Validation and correction of Zn–Cys(x)His(y) complexes
por: Touw, Wouter G., et al.
Publicado: (2016)

Induction of Gliotoxin Secretion in Aspergillus fumigatus by Bacteria-Associated Molecules
por: Svahn, K. Stefan, et al.
Publicado: (2014)

Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells
por: Chen, Junxiong, et al.
Publicado: (2015)

Novel Action Targets of Natural Product Gliotoxin in Photosynthetic Apparatus
por: Guo, Yanjing, et al.
Publicado: (2020)

Enlightening Gliotoxin Biological System in Agriculturally Relevant Trichoderma spp.
por: Bulgari, Daniela, et al.
Publicado: (2020)

Familial MTC with RET exon 8 Gly533Cys mutation: origin and prevalence of second malignancy
por: Saltiki, Katerina, et al.
Publicado: (2017)

Improved Quasi-Z-Source High Step-Up DC–DC Converter Based on Voltage-Doubler Topology
por: Sai, Toru, et al.
Publicado: (2022)

Preparation of Zn−Gly and Se−Gly and Their Effects on the Nutritional Quality of Tea (Camellia sinensis)
por: Li, Feixia, et al.
Publicado: (2023)

Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus
por: Dolan, Stephen K., et al.
Publicado: (2017)

Vacuoles and peroxisomes are involved in Aspergillus fumigatus gliotoxin production and self-protection
por: de Castro, Patrícia Alves, et al.
Publicado: (2023)

Molecular characterization of gliotoxin-producing Aspergillus fumigatus in dairy cattle feed
por: Mohamed, Hams M. A., et al.
Publicado: (2023)

Structure-based analysis of CysZ-mediated cellular uptake of sulfate
por: Assur Sanghai, Zahra, et al.
Publicado: (2018)

ZCF32, a fungus specific Zn(II)2 Cys6 transcription factor, is a repressor of the biofilm development in the human pathogen Candida albicans
por: Kakade, Pallavi, et al.
Publicado: (2016)

Crystal structures of Z–Gly–Aib–O(−)·0.5Ca(2+)·H(2)O and Z–Gly–Aib–OH
por: Gessmann, Renate, et al.
Publicado: (2018)

The biosynthetic pathway of 2-azahypoxanthine in fairy-ring forming fungus
por: Suzuki, Tomohiro, et al.
Publicado: (2016)

Chemical, Bioactivity, and Biosynthetic Screening of Epiphytic Fungus Zasmidium pseudotsugae
por: González-Montiel, Gisela A., et al.
Publicado: (2020)

Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling
por: WANG, GUANGYE, et al.
Publicado: (2015)

In vitro activity of chlorogenic acid against Aspergillus fumigatus biofilm and gliotoxin production
por: Kong, Jin-Liang, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lsj2lm6esordhooanm66qm4a2d