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Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence

Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the ne...

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Detalles Bibliográficos
Autores principales: Menditto, Enrica, Orlando, Valentina, De Rosa, Giuseppe, Minghetti, Paola, Musazzi, Umberto Maria, Cahir, Caitriona, Kurczewska-Michalak, Marta, Kardas, Przemysław, Costa, Elísio, Sousa Lobo, José Manuel, Almeida, Isabel F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023035/
https://www.ncbi.nlm.nih.gov/pubmed/31947888
http://dx.doi.org/10.3390/pharmaceutics12010044
Descripción
Sumario:Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the needs of the patients. In particular, geriatric and paediatric populations as well as dermatological patients have special needs/preferences that should be considered when designing drug products. Patient Centric Drug Product Pharmaceutical Design (PCDPD) offers the opportunity to meet the needs and preferences of patients. Packaging, orodispersible formulations, fixed dose combinations products, multiparticulate formulations, topical formulations and 3D printing are of particular relevance in a PCDPD process. These will be addressed in this review as well as their impact on medication adherence.