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Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence

Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the ne...

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Autores principales: Menditto, Enrica, Orlando, Valentina, De Rosa, Giuseppe, Minghetti, Paola, Musazzi, Umberto Maria, Cahir, Caitriona, Kurczewska-Michalak, Marta, Kardas, Przemysław, Costa, Elísio, Sousa Lobo, José Manuel, Almeida, Isabel F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023035/
https://www.ncbi.nlm.nih.gov/pubmed/31947888
http://dx.doi.org/10.3390/pharmaceutics12010044
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author Menditto, Enrica
Orlando, Valentina
De Rosa, Giuseppe
Minghetti, Paola
Musazzi, Umberto Maria
Cahir, Caitriona
Kurczewska-Michalak, Marta
Kardas, Przemysław
Costa, Elísio
Sousa Lobo, José Manuel
Almeida, Isabel F
author_facet Menditto, Enrica
Orlando, Valentina
De Rosa, Giuseppe
Minghetti, Paola
Musazzi, Umberto Maria
Cahir, Caitriona
Kurczewska-Michalak, Marta
Kardas, Przemysław
Costa, Elísio
Sousa Lobo, José Manuel
Almeida, Isabel F
author_sort Menditto, Enrica
collection PubMed
description Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the needs of the patients. In particular, geriatric and paediatric populations as well as dermatological patients have special needs/preferences that should be considered when designing drug products. Patient Centric Drug Product Pharmaceutical Design (PCDPD) offers the opportunity to meet the needs and preferences of patients. Packaging, orodispersible formulations, fixed dose combinations products, multiparticulate formulations, topical formulations and 3D printing are of particular relevance in a PCDPD process. These will be addressed in this review as well as their impact on medication adherence.
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spelling pubmed-70230352020-03-12 Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence Menditto, Enrica Orlando, Valentina De Rosa, Giuseppe Minghetti, Paola Musazzi, Umberto Maria Cahir, Caitriona Kurczewska-Michalak, Marta Kardas, Przemysław Costa, Elísio Sousa Lobo, José Manuel Almeida, Isabel F Pharmaceutics Review Medication adherence is a growing concern for public health and poor adherence to therapy has been associated with poor health outcomes and higher costs for patients. Interventions for improving adherence need to consider the characteristics of the individual therapeutic regimens according to the needs of the patients. In particular, geriatric and paediatric populations as well as dermatological patients have special needs/preferences that should be considered when designing drug products. Patient Centric Drug Product Pharmaceutical Design (PCDPD) offers the opportunity to meet the needs and preferences of patients. Packaging, orodispersible formulations, fixed dose combinations products, multiparticulate formulations, topical formulations and 3D printing are of particular relevance in a PCDPD process. These will be addressed in this review as well as their impact on medication adherence. MDPI 2020-01-03 /pmc/articles/PMC7023035/ /pubmed/31947888 http://dx.doi.org/10.3390/pharmaceutics12010044 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Menditto, Enrica
Orlando, Valentina
De Rosa, Giuseppe
Minghetti, Paola
Musazzi, Umberto Maria
Cahir, Caitriona
Kurczewska-Michalak, Marta
Kardas, Przemysław
Costa, Elísio
Sousa Lobo, José Manuel
Almeida, Isabel F
Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
title Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
title_full Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
title_fullStr Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
title_full_unstemmed Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
title_short Patient Centric Pharmaceutical Drug Product Design—The Impact on Medication Adherence
title_sort patient centric pharmaceutical drug product design—the impact on medication adherence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023035/
https://www.ncbi.nlm.nih.gov/pubmed/31947888
http://dx.doi.org/10.3390/pharmaceutics12010044
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