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Effect of Formulation Factors and Oxygen Levels on the Stability of Aqueous Injectable Solution Containing Pemetrexed

The aim of this study was to investigate the effects of various parameters at each control strategy in drug product degradation on the stability of pemetrexed in injectable aqueous solution. A forced degradation study confirmed that oxidation is the main mechanism responsible for the degradation of...

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Detalles Bibliográficos
Autores principales:	Won, Dong Han, Park, Heejun, Ha, Eun-Sol, Kim, Yong Min, Hwang, Hyung Don, Jang, Sun Woo, Kim, Min-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023127/ https://www.ncbi.nlm.nih.gov/pubmed/31935808 http://dx.doi.org/10.3390/pharmaceutics12010046

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