Cargando…

ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (Geno)Toxicity Screening of Nanoparticles—Metals, Oxides and Quantum Dots

The increased use of nanoparticles (NPs) requires efficient testing of their potential toxic effects. A promising approach is to use reporter cell lines to quickly assess the activation of cellular stress response pathways. This study aimed to use the ToxTracker reporter cell lines to investigate (g...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCarrick, Sarah, Cappellini, Francesca, Kessler, Amanda, Moelijker, Nynke, Derr, Remco, Hedberg, Jonas, Wold, Susanna, Blomberg, Eva, Odnevall Wallinder, Inger, Hendriks, Giel, Karlsson, Hanna L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023144/ https://www.ncbi.nlm.nih.gov/pubmed/31935871 http://dx.doi.org/10.3390/nano10010110

Ejemplares similares

Genotoxic and mutagenic properties of Ni and NiO nanoparticles investigated by comet assay, γ‐H2AX staining, Hprt mutation assay and ToxTracker reporter cell lines
por: Åkerlund, Emma, et al.
Publicado: (2017)

Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines
por: Karlsson, Hanna L, et al.
Publicado: (2014)

The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols
por: Czekala, Lukasz, et al.
Publicado: (2021)

Adsorption of Horseradish Peroxidase on Metallic Nanoparticles: Effects on Reactive Oxygen Species Detection Using 2′,7′-Dichlorofluorescin Diacetate
por: Kessler, Amanda, et al.
Publicado: (2021)

Empirical comparison of genotoxic potency estimations: the in vitro DNA-damage ToxTracker endpoints versus the in vivo micronucleus assay
por: Wills, John W, et al.
Publicado: (2021)

Effect of sonication on particle dispersion, administered dose and metal release of non-functionalized, non-inert metal nanoparticles
por: Pradhan, Sulena, et al.
Publicado: (2016)

Influence of Biocorona Formation on the Transformation and Dissolution of Cobalt Nanoparticles under Physiological Conditions
por: Mei, Nanxuan, et al.
Publicado: (2019)

Influence of humic acid and dihydroxy benzoic acid on the agglomeration, adsorption, sedimentation and dissolution of copper, manganese, aluminum and silica nanoparticles – A tentative exposure scenario
por: Pradhan, Sulena, et al.
Publicado: (2018)

Difficulties and flaws in performing accurate determinations of zeta potentials of metal nanoparticles in complex solutions—Four case studies
por: Skoglund, Sara, et al.
Publicado: (2017)

Chromium released from leather – I: exposure conditions that govern the release of chromium(III) and chromium(VI)
por: Hedberg, Yolanda S, et al.
Publicado: (2015)

Bioaccessibility of Nickel and Cobalt Released from Occupationally Relevant Alloy and Metal Powders at Simulated Human Exposure Scenarios
por: Wang, Xuying, et al.
Publicado: (2020)

Bioaccessibility, bioavailability and toxicity of commercially relevant iron- and chromium-based particles: in vitro studies with an inhalation perspective
por: Hedberg, Yolanda, et al.
Publicado: (2010)

Reactive Oxygen Species Formed by Metal and Metal Oxide Nanoparticles in Physiological Media—A Review of Reactions of Importance to Nanotoxicity and Proposal for Categorization
por: Kessler, Amanda, et al.
Publicado: (2022)

Optimization of an air–liquid interface exposure system for assessing toxicity of airborne nanoparticles
por: Latvala, Siiri, et al.
Publicado: (2016)

Surface-protein interactions on different stainless steel grades: effects of protein adsorption, surface changes and metal release
por: Hedberg, Y., et al.
Publicado: (2013)

Genotoxicity and inflammatory potential of stainless steel welding fume particles: an in vitro study on standard vs Cr(VI)-reduced flux-cored wires and the role of released metals
por: McCarrick, Sarah, et al.
Publicado: (2021)

Dry Generation of CeO(2) Nanoparticles and Deposition onto a Co-Culture of A549 and THP-1 Cells in Air-Liquid Interface—Dosimetry Considerations and Comparison to Submerged Exposure
por: Cappellini, Francesca, et al.
Publicado: (2020)

A comparison of classical and 21st century genotoxicity tools: A proof of concept study of 18 chemicals comparing in vitro micronucleus, ToxTracker and genomics‐based methods (TGx‐DDI, whole genome clustering and connectivity mapping)
por: Allemang, Ashley, et al.
Publicado: (2020)

Mechanistic insight on the combined effect of albumin and hydrogen peroxide on surface oxide composition and extent of metal release from Ti6Al4V
por: Hedberg, Yolanda S., et al.
Publicado: (2018)

Transformation of silver nanoparticles released from skin cream and mouth spray in artificial sweat and saliva solutions: particle size, dissolution, and surface area
por: Hedberg, Jonas, et al.
Publicado: (2020)

Nickel Release, ROS Generation and Toxicity of Ni and NiO Micro- and Nanoparticles
por: Latvala, Siiri, et al.
Publicado: (2016)

Can gamma irradiation during radiotherapy influence the metal release process for biomedical CoCrMo and 316L alloys?
por: Wei, Zheng, et al.
Publicado: (2018)

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release
por: Gliga, Anda R, et al.
Publicado: (2014)

Adsorption of bio-organic eco-corona molecules reduces the toxic response to metallic nanoparticles in Daphnia magna
por: Ekvall, Mikael T., et al.
Publicado: (2021)

Release of Si from Silicon, a Ferrosilicon (FeSi) Alloy and a Synthetic Silicate Mineral in Simulated Biological Media
por: Herting, Gunilla, et al.
Publicado: (2014)

Modelled lung deposition and retention of welding fume particles in occupational scenarios: a comparison to doses used in vitro
por: McCarrick, Sarah, et al.
Publicado: (2022)

Corrosion and transformation of solution combustion synthesized Co, Ni and CoNi nanoparticles in synthetic freshwater with and without natural organic matter
por: Khort, Alexander, et al.
Publicado: (2021)

Calcium-dependent cyto- and genotoxicity of nickel metal and nickel oxide nanoparticles in human lung cells
por: Di Bucchianico, Sebastiano, et al.
Publicado: (2018)

Silver nanoparticles modulate lipopolysaccharide-triggered Toll-like receptor signaling in immune-competent human cell lines
por: Gliga, Anda R., et al.
Publicado: (2020)

Presence of impurities of nickel and cobalt in facial cosmetic pigments and their dissolution into artificial sweat
por: Wang, Xuying, et al.
Publicado: (2022)

Writing DNA with GenoCAD™
por: Czar, Michael J., et al.
Publicado: (2009)

ArrhythmoGenoPharmacoTherapy
por: Tosaki, Arpad
Publicado: (2020)

Gold Nanoparticles Dissolve Extracellularly in the Presence of Human Macrophages
por: McCarrick, Sarah, et al.
Publicado: (2021)

The Effect of Trapped Backstreaming Ions on Beam Focus and Emittance in Radiographic Accelerators
por: Houck, T L, et al.
Publicado: (1999)

Perseverative Cognition and Snack Choice: An Online Pilot Investigation
por: Eschle, Timothy M., et al.
Publicado: (2021)

A novel methodology to study antimicrobial properties of high-touch surfaces used for indoor hygiene applications—A study on Cu metal
por: Chang, T., et al.
Publicado: (2021)

Analysis of Historic Copper Patinas. Influence of Inclusions on Patina Uniformity
por: Chang, Tingru, et al.
Publicado: (2017)

On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens
por: Janesick, Amanda Shaine, et al.
Publicado: (2016)

Atomistic Analysis of ToxN and ToxI Complex Unbinding Mechanism
por: Hu, Guodong, et al.
Publicado: (2018)

Home advantage during the COVID-19 pandemic: Analyses of European football leagues
por: McCarrick, Dane, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kg6grhgvso2h3cu9cq0mrj8m60