3,3′-Diindolylmethane Promotes BDNF and Antioxidant Enzyme Formation via TrkB/Akt Pathway Activation for Neuroprotection against Oxidative Stress-Induced Apoptosis in Hippocampal Neuronal Cells

3,3′-Diindolylmethane (DIM), a metabolite of indole-3-carbinol present in Brassicaceae vegetables, possesses various health-promoting effects. Nonetheless, the effect of DIM on neurodegenerative diseases has not been elucidated clearly. In this study, we hypothesized DIM may protect neuronal cells a...

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Detalles Bibliográficos
Autores principales: Lee, Bo Dam, Yoo, Jae-Myung, Baek, Seong Yeon, Li, Fu Yi, Sok, Dai-Eun, Kim, Mee Ree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023184/
https://www.ncbi.nlm.nih.gov/pubmed/31861353
http://dx.doi.org/10.3390/antiox9010003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023184/
https://www.ncbi.nlm.nih.gov/pubmed/31861353
http://dx.doi.org/10.3390/antiox9010003

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