Cargando…

Polymer Cancerostatics Containing Cell-Penetrating Peptides: Internalization Efficacy Depends on Peptide Type and Spacer Length

Cell-penetrating peptides (CPPs) are commonly used substances enhancing the cellular uptake of various cargoes that do not easily cross the cellular membrane. CPPs can be either covalently bound directly to the cargo or they can be attached to a transporting system such as a polymer carrier together...

Descripción completa

Detalles Bibliográficos
Autores principales:	Böhmová, Eliška, Pola, Robert, Pechar, Michal, Parnica, Jozef, Machová, Daniela, Janoušková, Olga, Etrych, Tomáš
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023232/ https://www.ncbi.nlm.nih.gov/pubmed/31936737 http://dx.doi.org/10.3390/pharmaceutics12010059

Ejemplares similares

Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors
por: Pola, Robert, et al.
Publicado: (2020)

Polymer-Antimicrobial Peptide Constructs with Tailored Drug-Release Behavior
por: Pola, Robert, et al.
Publicado: (2023)

Fluorescence Imaging as a Tool in Preclinical Evaluation of Polymer-Based Nano-DDS Systems Intended for Cancer Treatment
por: Etrych, Tomáš, et al.
Publicado: (2019)

Octahedral Molybdenum Cluster-Based Nanomaterials for Potential Photodynamic Therapy
por: Tavares, Marina Rodrigues, et al.
Publicado: (2022)

Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice.
por: Fodstad, O., et al.
Publicado: (1976)

Structure-to-Efficacy Relationship of HPMA-Based Nanomedicines: The Tumor Spheroid Penetration Study
por: Kudláčová, Júlia, et al.
Publicado: (2020)

Influence of cancerostatic perifosine on membrane fluidity of liposomes and different cell lines as measured by electron paramagnetic resonance
por: Podlipec, Rok, et al.
Publicado: (2012)

Anti-Lymphoma Efficacy Comparison of Anti-CD20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates
por: Lidický, Ondřej, et al.
Publicado: (2015)

Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells
por: Kalousková, Barbora, et al.
Publicado: (2021)

Tumor-Penetrating Peptides
por: Teesalu, Tambet, et al.
Publicado: (2013)

Cell-Penetrating Peptides and Transportan
por: Langel, Ülo
Publicado: (2021)

Effect of inserted spacer in hepatic cell-penetrating multifunctional peptide component on the DNA intracellular delivery of quaternary complexes based on modular design
por: Zhang, Luchen, et al.
Publicado: (2016)

Disruptin, a cell-penetrating peptide degrader of EGFR: Cell-Penetrating Peptide in Cancer Therapy
por: Mehta, Ranjit K., et al.
Publicado: (2021)

Peptide-Appended Permethylated β-Cyclodextrins with Hydrophilic and Hydrophobic Spacers
por: Al Temimi, Abbas H. K., et al.
Publicado: (2017)

Silver Nanoparticles Stabilised by Cationic Gemini Surfactants with Variable Spacer Length
por: Pisárčik, Martin, et al.
Publicado: (2017)

Therapeutic Potential of Cell Penetrating Peptides (CPPs) and Cationic Polymers for Chronic Hepatitis B
por: Ndeboko, Bénédicte, et al.
Publicado: (2015)

Prediction of Cell-Penetrating Potential of Modified Peptides Containing Natural and Chemically Modified Residues
por: Kumar, Vinod, et al.
Publicado: (2018)

Amphiphilic Cell-Penetrating Peptides Containing Arginine and Hydrophobic Residues as Protein Delivery Agents
por: Moreno, Jonathan, et al.
Publicado: (2023)

Cell Penetrating Peptides in the Delivery of Biopharmaceuticals
por: Munyendo, Were LL, et al.
Publicado: (2012)

Internalization mechanisms of cell-penetrating peptides
por: Ruseska, Ivana, et al.
Publicado: (2020)

Selective Moonlighting Cell-Penetrating Peptides
por: Morán-Torres, Rafael, et al.
Publicado: (2021)

Potent Activity of Hybrid Arthropod Antimicrobial Peptides Linked by Glycine Spacers
por: Tonk, Miray, et al.
Publicado: (2021)

Enhancing the biological activity of polyoxometalate–peptide nano-fibrils by spacer design
por: Tagliavini, Valeria, et al.
Publicado: (2021)

Peptide-Ligand Binding Modeling of siRNA with Cell-Penetrating Peptides
por: García-Sosa, Alfonso T., et al.
Publicado: (2014)

Conjugation of Cell-Penetrating Peptides to Antimicrobial Peptides Enhances Antibacterial Activity
por: Lee, Hyunhee, et al.
Publicado: (2019)

Antimicrobial Peptides and Cell-Penetrating Peptides for Treating Intracellular Bacterial Infections
por: Buccini, Danieli F., et al.
Publicado: (2021)

Amphiphilic Cell-Penetrating Peptides Containing Natural and Unnatural Amino Acids as Drug Delivery Agents
por: Salehi, David, et al.
Publicado: (2022)

Effects of the properties of short peptides conjugated with cell-penetrating peptides on their internalization into cells
por: Matsumoto, Ryo, et al.
Publicado: (2015)

Fluorophore-Tagged Poly-Lysine RAFT Agents: Controlled Synthesis of Trackable Cell-Penetrating Peptide–Polymers
por: Shaw, Paige A., et al.
Publicado: (2023)

Mechanisms of Cellular Uptake of Cell-Penetrating Peptides
por: Madani, Fatemeh, et al.
Publicado: (2011)

Cell-Penetrating Peptides for Antiviral Drug Development
por: Delcroix, Melaine, et al.
Publicado: (2010)

Membranotropic Cell Penetrating Peptides: The Outstanding Journey
por: Falanga, Annarita, et al.
Publicado: (2015)

Chemical-Functional Diversity in Cell-Penetrating Peptides
por: Stalmans, Sofie, et al.
Publicado: (2013)

Delivery of therapeutic oligonucleotides with cell penetrating peptides()
por: Boisguérin, Prisca, et al.
Publicado: (2015)

The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides
por: Pärn, Kalle, et al.
Publicado: (2015)

Construction of histidine-containing hydrocarbon stapled cell penetrating peptides for in vitro and in vivo delivery of siRNAs
por: Hyun, Soonsil, et al.
Publicado: (2018)

Chiral Cyclobutane-Containing Cell-Penetrating Peptides as Selective Vectors for Anti-Leishmania Drug Delivery Systems
por: Illa, Ona, et al.
Publicado: (2020)

Molecular dynamics study of the internalization of cell-penetrating peptides containing unnatural amino acids across membranes
por: Gimenez-Dejoz, Joan, et al.
Publicado: (2021)

Antimicrobial and Cell-Penetrating Peptides: Understanding Penetration for the Design of Novel Conjugate Antibiotics
por: Hadjicharalambous, Andreas, et al.
Publicado: (2022)

Delivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold
por: Zhao, Xing-Liang, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_khms1ol72p7nc9hchrs18rr94i