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Computer-Aided Design of Cefuroxime Axetil/Cyclodextrin System with Enhanced Solubility and Antimicrobial Activity

This study aimed to investigate changes in the solubility and antimicrobial efficacy of cefuroxime axetil (CA) when incorporated into cyclodextrin (CD). While choosing the CD, the validated in silico model was used. A theoretical model based on docking and molecular mechanics/generalized born surfac...

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Detalles Bibliográficos
Autores principales:	Mizera, Mikołaj, Szymanowska, Daria, Stasiłowicz, Anna, Siąkowska, Dominika, Lewandowska, Kornelia, Miklaszewski, Andrzej, Plech, Tomasz, Tykarska, Ewa, Cielecka-Piontek, Judyta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023374/ https://www.ncbi.nlm.nih.gov/pubmed/31878057 http://dx.doi.org/10.3390/biom10010024

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