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Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions

The critical CO(2) hydration reaction to bicarbonate and protons is catalyzed by carbonic anhydrases (CAs, EC 4.2.1.1). Their physiological role is to assist the transport of the CO(2) and HCO(3)(−) at the cellular level, which will not be ensured by the low velocity of the uncatalyzed reaction. CA...

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Detalles Bibliográficos
Autores principales: Del Prete, Sonia, Angeli, Andrea, Ghobril, Cynthia, Hitce, Julien, Clavaud, Cécile, Marat, Xavier, Supuran, Claudiu T., Capasso, Clemente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023381/
https://www.ncbi.nlm.nih.gov/pubmed/31963335
http://dx.doi.org/10.3390/metabo10010039