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Sulfonamide Inhibition Profile of the β-Carbonic Anhydrase from Malassezia restricta, An Opportunistic Pathogen Triggering Scalp Conditions
The critical CO(2) hydration reaction to bicarbonate and protons is catalyzed by carbonic anhydrases (CAs, EC 4.2.1.1). Their physiological role is to assist the transport of the CO(2) and HCO(3)(−) at the cellular level, which will not be ensured by the low velocity of the uncatalyzed reaction. CA...
Autores principales: | Del Prete, Sonia, Angeli, Andrea, Ghobril, Cynthia, Hitce, Julien, Clavaud, Cécile, Marat, Xavier, Supuran, Claudiu T., Capasso, Clemente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023381/ https://www.ncbi.nlm.nih.gov/pubmed/31963335 http://dx.doi.org/10.3390/metabo10010039 |
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