Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats

Recently, various types of cultured cells have been used to research the mechanisms of transport and metabolism of drugs. Although many studies using cultured cell systems have been published, a comparison of different cultured cell systems has never been reported. In this study, Caco-2, Calu-3, Mad...

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Detalles Bibliográficos
Autores principales: Furubayashi, Tomoyuki, Inoue, Daisuke, Nishiyama, Noriko, Tanaka, Akiko, Yutani, Reiko, Kimura, Shunsuke, Katsumi, Hidemasa, Yamamoto, Akira, Sakane, Toshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023391/
https://www.ncbi.nlm.nih.gov/pubmed/31963555
http://dx.doi.org/10.3390/pharmaceutics12010079

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