In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

Enhancing the oral bioavailability of peptides has received a lot of attention for decades but remains challenging, partly due to low intestinal membrane permeability. Combining a permeation enhancer (PE) with unidirectionally releasing microcontainers (MCs) has previously been shown to increase ins...

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Detalles Bibliográficos
Autores principales: Jørgensen, Jacob Rune, Yu, Feiyang, Venkatasubramanian, Ramakrishnan, Nielsen, Line Hagner, Nielsen, Hanne Mørck, Boisen, Anja, Rades, Thomas, Müllertz, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023435/
https://www.ncbi.nlm.nih.gov/pubmed/31936066
http://dx.doi.org/10.3390/pharmaceutics12010048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023435/
https://www.ncbi.nlm.nih.gov/pubmed/31936066
http://dx.doi.org/10.3390/pharmaceutics12010048

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