Cargando…
Actively Targeted and Redox Responsive Delivery of Anticancer Drug by Chitosan Nanoparticles
The clinical efficacy of methotrexate (MTX) is limited by its poor water solubility, its low bioavailability, and the development of resistance in cancer cells. Herein, we developed novel folate redox-responsive chitosan (FTC) nanoparticles for intracellular MTX delivery. l-Cysteine and folic acid m...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023447/ https://www.ncbi.nlm.nih.gov/pubmed/31888000 http://dx.doi.org/10.3390/pharmaceutics12010026 |